For the first time, scientists have visualized a new class of molecular gates that maintain pH balance within brain cells, a critical function that keeps cells alive and helps prevent stroke and other brain injuries. These gates, called proton-activated chloride channels (PAC), nest within cell membranes and regulate the passage of small molecules called chloride ions into and out of cells. This allows cells to sense and respond to their environment.
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Near-atomic ‘maps’ reveal structure for maintaining pH balance in cells
November 5, 2020By
Researchers Identify Key Structure of C. Difficle Bacteria That Could Lead to Future Treatments
January 3, 2020By
– Researchers from the University of Maryland School of Medicine and their colleagues have identified the structure of the most lethal toxin produced by certain strains of Clostridium difficile bacteria, a potentially deadly infection associated with the use of antibiotics. The researchers mapped out the delivery and binding components of the toxin, which could pave the way for new drugs to neutralize it.
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New Algorithms Shed Light on Molecules’ Structure and Motion in Cells
December 21, 2019By
To understand why very large molecules behave the way they do inside cells, scientists must first understand the relationship between these molecules’ structure and motion. Engineers created algorithms that provide the physics backbone for a new “microscope in a computer.”
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Researchers validate optimum composites structure created with additive manufacturing
June 28, 2019By
Creating objects out of polymers using additive manufacturing techniques is perfect for a prototype, but not for structural materials that require strength or stiffness. A new trend is to use polymer composite materials reinforced with carbon fibers, much like rebar in a cement sidewalk. The question is, what pattern of carbon fibers results in the stiffest material.
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Gut microbes linked to brain structure in people with irritable bowel syndrome
May 6, 2017By
Research shows for the first time an association between the gut microbiota and the brain regions involved in the processing of sensory information from their bodies. Also, the researchers gained insight into the connections among childhood trauma, brain development and gut microbiome composition.
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